Product Info Summary
SKU: | A00902 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IF, WB |
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Product info
Product Name
Anti-MLTK MAP3K20 Antibody
SKU/Catalog Number
A00902
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-MLTK MAP3K20 Antibody (Catalog # A00902). Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MLTK MAP3K20 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00902)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human MLTK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00902 is reactive to MAP3K20 in Human, Mouse
Reconstitution
Calculated molecular weight
91155 MW
Background of MAP3K20
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
Gotoh I., J. Biol. Chem. 276:4276-4286(2001).
Bloem L.J., J. Mol. Cell. Cardiol. 33:1739-1750(2001).
Gross E.A., J. Biol. Chem. 277:13873-13882(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00902 is guaranteed for IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from HeLa cells, using MLTK antibody A00902.
Click image to see more details
Immunofluorescence analysis of HepG2 cells, using MLTK antibody A00902.
Protein Target Info & Infographic
Gene/Protein Information For MAP3K20 (Source: Uniprot.org, NCBI)
Gene Name
MAP3K20
Full Name
Mitogen-activated protein kinase kinase kinase 20
Weight
91155 MW
Superfamily
protein kinase superfamily
Alternative Names
Mitogen-activated protein kinase kinase kinase MLT;2.7.11.25;Human cervical cancer suppressor gene 4 protein;HCCS-4;Leucine zipper- and sterile alpha motif-containing kinase;MLK-like mitogen-activated protein triple kinase;Mixed lineage kinase-related kinase;MLK-related kinase;MRK;Sterile alpha motif- and leucine zipper-containing kinase AZK;ZAK;MLTK;HCCS4; MAP3K20 AZK, CNM6, MLK7, MLT, MLTK, MLTKalpha, MLTKbeta, MRK, SFMMP, ZAK, mlklak, pk mitogen-activated protein kinase kinase kinase 20 mitogen-activated protein kinase kinase kinase 20|HCCS-4|MLK-like mitogen-activated protein triple kinase|ZAK1 homolog, leucine zipper and sterile-alpha motif kinase|human cervical cancer suppressor gene 4 protein|mitogen-activated protein kinase kinase kinase MLT|mixed lineage kinase 7|mixed lineage kinase with a leucine zipper and a sterile alpha motif|mixed lineage kinase-related kinase MRK-beta|sterile alpha motif and leucine zipper containing kinase AZK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAP3K20, check out the MAP3K20 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAP3K20: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MLTK MAP3K20 Antibody (A00902)
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No publications found for A00902
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