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- Table of Contents
Facts about Mitogen-activated protein kinase kinase kinase 20.
Section of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and contributes to the activation of MAPK14. Pro-apoptotic.
Human | |
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Gene Name: | MAP3K20 |
Uniprot: | Q9NYL2 |
Entrez: | 51776 |
Belongs to: |
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protein kinase superfamily |
Mitogen-activated protein kinase kinase kinase 20
Mass (kDA):
91.155 kDA
Human | |
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Location: | 2q31.1 |
Sequence: | 2; NC_000002.12 (173075435..173268015) |
Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.
Cytoplasm. Nucleus. Translocates to the nucleus upon ultraviolet B irradiation.
PMID: 10924358 by Liu T.-C., et al. Cloning and expression of ZAK, a mixed lineage kinase-like protein containing a leucine-zipper and a sterile-alpha motif.
PMID: 11042189 by Gotoh I., et al. Identification and characterization of a novel MAP kinase kinase kinase, MLTK.