Click image to see more details
Product Info Summary
| SKU: | A09965 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-MICOS complex subunit MIC25 CHCHD6 Antibody
SKU/Catalog Number
A09965
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (Catalog # A09965). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
CHCHD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09965)
Host
Rabbit
Contents
CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6. The immunogen is located within amino acids 20 - 70 of CHCHD6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CHCHD6 is predicted to not cross-react to other members of the CHCHD family.
Reactive Species
A09965 is reactive to CHCHD6 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
26458 MW
Background of Chchd6
CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09965 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CHCHD6 in SK-N-SH cell lysate with CHCHD6 antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CHCHD6 (Source: Uniprot.org, NCBI)
Gene Name
CHCHD6
Full Name
MICOS complex subunit Mic25
Weight
26458 MW
Superfamily
MICOS complex subunit Mic19 family
Alternative Names
CHCM1, PPP1R23, CHCM1, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial, Coiled coil helix cristae morphology protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CHCHD6, check out the CHCHD6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CHCHD6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MICOS complex subunit MIC25 CHCHD6 Antibody (A09965)
Hello CJ!
No publications found for A09965
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-MICOS complex subunit MIC25 CHCHD6 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-MICOS complex subunit MIC25 CHCHD6 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
