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Product Info Summary
| SKU: | A08410 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Metalloreductase STEAP2 STEAP2 Antibody
SKU/Catalog Number
A08410
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Metalloreductase STEAP2 STEAP2 Antibody (Catalog # A08410). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
STEAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Metalloreductase STEAP2 STEAP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08410)
Host
Rabbit
Contents
STEAP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
STEAP2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human STEAP2. The immunogen is located within the last 50 amino acids of STEAP2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This STEAP2 antibody does not cross-react with other STEAP proteins.
Reactive Species
A08410 is reactive to Steap2 in Human, Mouse
Applications
A08410 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
56056 MW
Background of Steap2
The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
STEAP2 antibody can be used for detection of STEAP2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of STEAP2 in human prostate tissue lysate with STEAP2 antibody at 1 μg/mL.
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Immunohistochemistry of STEAP2 in human colon tissue with STEAP2 antibody at 2.5 μg/mL.
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Immunofluorescence of STEAP2 in Human Colon cells with STEAP2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Steap2 (Source: Uniprot.org, NCBI)
Gene Name
Steap2
Full Name
Metalloreductase STEAP2
Weight
56056 MW
Superfamily
STEAP family
Alternative Names
EC 1.16.1; EC 1.16.1.-; IPCA1; metalloreductase STEAP2; PCANAP1; PCANAP1STMP; prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1; STAMP1; STAMP1IPCA-1; STEAP2; STMP Steap2|4921538B17Rik, AI930049, AW045895, IPCA-1, IPCA1, PCANAP1, STAMP1, STMP|six transmembrane epithelial antigen of prostate 2|metalloreductase STEAP2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Steap2, check out the Steap2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Steap2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Metalloreductase STEAP2 STEAP2 Antibody (A08410)
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