Click image to see more details
Product Info Summary
| SKU: | A07506 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-Metalloreductase STEAP1 STEAP1 Antibody
SKU/Catalog Number
A07506
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Metalloreductase STEAP1 STEAP1 Antibody (Catalog # A07506). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
STEAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Metalloreductase STEAP1 STEAP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07506)
Host
Rabbit
Contents
STEAP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
STEAP1 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STEAP1. The immunogen is located within the last 50 amino acids of STEAP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This STEAP1 antibody does not cross-react with other STEAP proteins.
Reactive Species
A07506 is reactive to STEAP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
39851 MW
Background of STEAP1
The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07506 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
STEAP1 antibody can be used for detection of STEAP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of STEAP1 in human spleen tissue lysate with STEAP1 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of STEAP1 in human spleen tissue with STEAP1 antibody at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STEAP1 (Source: Uniprot.org, NCBI)
Gene Name
STEAP1
Full Name
Metalloreductase STEAP1
Weight
39851 MW
Superfamily
STEAP family
Alternative Names
STEAP, PRSS24, STEAP, Metalloreductase STEAP1, Six-transmembrane epithelial antigen of prostate 1 STEAP1 PRSS24, STEAP STEAP family member 1 metalloreductase STEAP1|STEAP1 metalloreductase|six transmembrane epithelial of the prostate 1|six-transmembrane epithelial of prostate 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STEAP1, check out the STEAP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STEAP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Metalloreductase STEAP1 STEAP1 Antibody (A07506)
Hello CJ!
No publications found for A07506
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-Metalloreductase STEAP1 STEAP1 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-Metalloreductase STEAP1 STEAP1 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
