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- Table of Contents
Facts about Metalloreductase STEAP1.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+).
Uses NAD(+) as acceptor (By similarity).. .
Human | |
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Gene Name: | STEAP1 |
Uniprot: | Q9UHE8 |
Entrez: | 26872 |
Belongs to: |
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STEAP family |
EC 1.16.1.-; PRSS24; PRSS24MGC19484; six transmembrane epithelial antigen of the prostate 1; six transmembrane epithelial antigen of the prostate; Six-transmembrane epithelial antigen of prostate 1; STEAP1; STEAPmetalloreductase STEAP1
Mass (kDA):
39.851 kDA
Human | |
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Location: | 7q21.13 |
Sequence: | 7; NC_000007.14 (90154469..90164827) |
Ubiquitously expressed. Highly expressed in prostate tumors.
Endosome membrane; Multi-pass membrane protein.
PMID: 10588738 by Hubert R.S., et al. STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
PMID: 16609065 by Ohgami R.S., et al. The Steap proteins are metalloreductases.