Anti-Monoamine Oxidase A/MAOA Antibody Picoband®

MAO-A antibody

Boster Bio Anti-Monoamine Oxidase A/MAOA Antibody Picoband® catalog # PB9664. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: PB9664
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IF, IHC, ICC, WB

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Product Name

Anti-Monoamine Oxidase A/MAOA Antibody Picoband®

View all MAO-A Antibodies

SKU/Catalog Number

PB9664

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Monoamine Oxidase A/MAOA Antibody Picoband® catalog # PB9664. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Monoamine Oxidase A/MAOA Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9664)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MAOA, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9664 is reactive to MAOA in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

60 kDa

Calculated molecular weight

59682 MW

Background of MAO-A

MAOA (Monoamine oxidase A), also known as AMINE OXIDASE (FLAVIN-CONTAINING) A, is an enzyme that in humans is encoded by the MAO-A gene. MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3. MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Inhibition of MAOA prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9664 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x106 cells, Human

Positive Control

WB: human RT4 whole cell, human HepG2 whole cell, rat liver tissue, mouse liver tissue
IHC: mouse cardiac muscle tissue, rat cardiac muscle tissue, human intestinal cancer tissue
ICC/IF: U20S cell
FCM: U87 cell, U20S cell

Validation Images & Assay Conditions

Gene/Protein Information For MAOA (Source: Uniprot.org, NCBI)

Gene Name

MAOA

Full Name

Amine oxidase [flavin-containing] A

Weight

59682 MW

Superfamily

flavin monoamine oxidase family

Alternative Names

Amine oxidase [flavin-containing] A;1.4.3.4;Monoamine oxidase type A;MAO-A;MAOA; MAOA BRNRS, MAO-A monoamine oxidase A amine oxidase [flavin-containing] A|monoamine oxidase type A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAOA, check out the MAOA Infographic

MAOA infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAOA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Monoamine Oxidase A/MAOA Antibody Picoband®

Question

We are currently using anti-Monoamine Oxidase A/MAOA antibody PB9664 for human tissue, and we are satisfied with the IHC-P results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on primate tissues as well?

Verified Customer

Verified customer

Asked: 2020-03-18

Answer

The anti-Monoamine Oxidase A/MAOA antibody (PB9664) has not been validated for cross reactivity specifically with primate tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-03-18

Order DetailsPrice
PB9664

100μg

$370
PB9664-10ug

10μg sample (liquid)

$99
PB9664-Biotin

100 μg Biotin conjugated

$570
PB9664-Cy3

100 μg Cy3 conjugated

$570
PB9664-Dylight488

100 μg Dylight488 conjugated

$570
PB9664-Dylight550

100 μg Dylight550 conjugated

$570
PB9664-Dylight594

100 μg Dylight594 conjugated

$570
PB9664-FITC

100 μg FITC conjugated

$570
PB9664-HRP

100 μg HRP conjugated

$570
PB9664-APC

100 μg APC conjugated

$670
PB9664-PE

100 μg PE conjugated

$670
PB9664-iFluor647

100 μg iFluor647 conjugated

$670
PB9664-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PB9664
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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