Anti-LRRC19 Antibody

Product Name

Anti-LRRC19 Antibody

View all LRRC19 Antibodies

SKU/Catalog Number

A15663

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-LRRC19 Antibody (Catalog # A15663). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-LRRC19 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15663)

Host

Rabbit

Contents

LRRC19 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

GLIPR1L2 antibody is human specific. At least two isoforms of GLIPR1L2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Reactive Species

A15663 is reactive to LRRC19 in Human, Mouse

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

42334 MW

Background of LRRC19

LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A15663 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For LRRC19 (Source: Uniprot.org, NCBI)

Alternative Names

Leucine-rich repeat-containing protein 19 LRRC19 leucine rich repeat containing 19 leucine-rich repeat-containing protein 19

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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