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Product Info Summary
| SKU: | A13956 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Lano LRRC1 Antibody
SKU/Catalog Number
A13956
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Lano LRRC1 Antibody (Catalog # A13956). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
Lano antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Lano LRRC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13956)
Host
Rabbit
Contents
Lano Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano. The immunogen is located within the last 50 amino acids of Lano.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody will not cross-react with the zinc transporter ZIP10.
Reactive Species
A13956 is reactive to LRRC1 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
59242 MW
Background of Lano
Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13956 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Lano antibody can be used for detection of Lano by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Lano expression in A431 cell lysate with Lano antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of Lano in human colon tissue with Lano antibody at 10 μg/mL.
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Immunofluorescence of Lano in human colon tissue with Lano antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For LRRC1 (Source: Uniprot.org, NCBI)
Gene Name
LRRC1
Full Name
Leucine-rich repeat-containing protein 1
Weight
59242 MW
Alternative Names
LANO, dJ523E19.1, LANO, Leucine-rich repeat-containing protein 1, LANO adapter protein LRRC1 LANO, dJ523E19.1 leucine rich repeat containing 1 leucine-rich repeat-containing protein 1|LANO adapter protein|LAP (leucine-rich repeats and PDZ) and no PDZ protein|LAP and no PDZ protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LRRC1, check out the LRRC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LRRC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Lano LRRC1 Antibody (A13956)
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