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Product Info Summary
| SKU: | M12092 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-KRT76 Antibody (Monoclonal, ABM51A8)
View all Cytokeratin, HMW Antibodies
SKU/Catalog Number
M12092
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-KRT76 Antibody (Monoclonal, ABM51A8) (Catalog# M12092). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-KRT76 Antibody (Monoclonal, ABM51A8) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M12092)
Host
Mouse
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Monoclonal
Clone Number
ABM51A8
Isotype
IgG2a lambda
Immunogen
A partial length recombinant protein of KRT76 (amino acid 145-362)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M12092 is reactive to KRT76 in Human
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
65841 MW
Background of Cytokeratin, HMW
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells.IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M12092 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot: 0.5-1 µg/ml
Validation Images & Assay Conditions
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Expression analysis of KRT76. Anti-KRT76 antibody (Clone: ABM51A8) was tested at 0.5 μg/ml on Hela, MCF7 and A431 lysates.
Protein Target Info & Infographic
Gene/Protein Information For KRT76 (Source: Uniprot.org, NCBI)
Gene Name
KRT76
Full Name
Keratin, type II cytoskeletal 2 oral
Weight
65841 MW
Superfamily
intermediate filament family
Alternative Names
Keratin, type II cytoskeletal 2 oral;Cytokeratin-2P;CK-2P;K2P;Keratin-76;K76;Type-II keratin Kb9;KRT76;KRT2B, KRT2P; KRT76 HUMCYT2A, KRT2B, KRT2P keratin 76 keratin, type II cytoskeletal 2 oral|CK-2P|K2P|K76|cytokeratin 2|cytokeratin-2P|keratin 2p|keratin 76, type II|type-II keratin Kb9
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KRT76, check out the KRT76 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KRT76: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KRT76 Antibody (Monoclonal, ABM51A8) (M12092)
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