Anti-Importin-9 Antibody

SKU A10216
Size 100 μg
Reactivity Human, Mouse
Clonality Polyclonal
Host Rabbit
Ig Isotype N/A
Applications IHC, WB

Overview

Product Name Anti-Importin-9 Antibody
SKU/Catalog Number A10216
Storage & Handling Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Size 100 μg
Description Rabbit IgG Polyclonal antibody for IPO9 detection. Tested with IHC, WB in Mouse, Human.
Cite This Product Anti-Importin-9 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10216)
Host Rabbit
Contents/Buffer 100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Form Liquid
Immunogen A partial length recombinant Importin-9 protein (amino acids 740-1,041).
Reactivity Human, Mouse

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Western blot analysis, 0.25-1.0 μg/ml
Immunohistochemical analysis, 5 μg/ml

Images And Assay Conditions

Immunohistochemical analysis of Importin-9. Anti-Importin-9 antibody (Respiratory Epithelium tissue at 5 μg/ml.

Immunohistochemical analysis of Importin-9. Anti-Importin-9 antibody in human Colon tissue at 5 μg/ml.

Western blot analysis of Importin-9. Anti- Importin-9 antibody was used at 0.25 μg/ml on 1) 293 and 2) 3T3 lysates.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id Q96P70
Gene Name IPO9
Protein Name Importin-9
Alternative Names Importin-9;Imp9;Ran-binding protein 9;RanBP9;IPO9;IMP9, KIAA1192, RANBP9;HSPC273;
Subcellular Localization Cytoplasm . Nucleus .
Molecular Weight 115963 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6. .
Research Areas Human, Mouse

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In stock
Order Product
A10216
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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