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Product Info Summary
| SKU: | A05271 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-ILPIP STRADB Antibody
SKU/Catalog Number
A05271
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ILPIP STRADB Antibody (Catalog # A05271). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ILPIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ILPIP STRADB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05271)
Host
Rabbit
Contents
ILPIP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ILPIP antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ILPIP. The immunogen is located within amino acids 280 - 330 of ILPIP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Depending on cell lines or tissues used, other cleavage products may be observed.
Reactive Species
A05271 is reactive to STRADB in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
47026 MW
Background of ALS2CR2
ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1β converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05271 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ILPIP antibody can be used for the detection of ILPIP by Western blot at 1 to 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ILPIP in human brain lysate with ILPIP antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ILPIP in human brain tissue with ILPIP antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STRADB (Source: Uniprot.org, NCBI)
Gene Name
STRADB
Full Name
STE20-related kinase adapter protein beta
Weight
47026 MW
Superfamily
protein kinase superfamily
Alternative Names
PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta STRADB ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038 STE20 related adaptor beta STE20-related kinase adapter protein beta|ILP-interacting protein ILPIPA|STE20-related kinase adaptor beta|STRAD beta|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein|pseudokinase ALS2CR2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STRADB, check out the STRADB Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STRADB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ILPIP STRADB Antibody (A05271)
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