Anti-IL3RA Antibody Picoband®

Product Name

Anti-IL3RA Antibody Picoband®

View all IL-3R alpha/CD123 Antibodies

SKU/Catalog Number

PA1617

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IL3RA Antibody catalog # PA1617. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IL3RA Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1617)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human IL3RA.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1617 is reactive to IL3RA in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

75 kDa

Calculated molecular weight

43330 MW

Background of IL-3R alpha/CD123

IL3RA (INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1617 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: A431 Cell, SMMC Cell, U87 Cell, 293T Cell,

Validation Images & Assay Conditions

Gene/Protein Information For IL3RA (Source: Uniprot.org, NCBI)

Alternative Names

Interleukin-3 receptor subunit alpha;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R-alpha;IL-3RA;CD123;IL3RA;IL3R; IL3RA CD123, IL3RY, IL3RX, IL3RY, hIL-3Ra, IL3RA interleukin 3 receptor subunit alpha interleukin-3 receptor subunit alpha|CD123 |IL-3 receptor subunit alpha|IL-3R subunit alpha|IL-3R-alpha|IL-3RA|interleukin 3 receptor, alpha (low affinity)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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