Anti-IL12A Mouse Monoclonal Antibody [Clone ID: OTI2A8]

Product Name

Anti-IL12A Mouse Monoclonal Antibody [Clone ID: OTI2A8]

View all IL12A Antibodies

SKU/Catalog Number

M00918

Size

100 µl

Description

Boster Bio IL12A mouse monoclonal antibody, clone OTI2A8 (formerly 2A8). Catalog# M00918. Tested in IHC, WB. This antibody reacts with Human.

Storage & Handling

Store at -20°C as received.

Cite This Product

Anti-IL12A Mouse Monoclonal Antibody [Clone ID: OTI2A8] (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00918)

Host

Mouse

Contents

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

OTI2A8

Isotype

IgG1

Immunogen

Human recombinant protein fragment corresponding to amino acids 57-253 of human IL12A (NP_000873) produced in E.coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00918 is reactive to IL12A in Human

Applications

M00918 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

Background of IL12A

Interleukin (IL)-12 is a 70-KDa cytokine comprised of two disulfide-linked proteins (p35 and p40) and is essential for the initiation of effective immune response.[i] And the IL-12p70 is a heterodimer of p35 and p40 subunits; it is an important cytokine secreted by antigen-presenting cells in response to antigenic stimulation.[ii] Gene expression analysis of the IL-12 cytokine family subunits revealed that both strains induced high levels of p40 (protein chain communal to IL-12 p70 and IL-23) as well as p19, a subunit of IL-23. Conversely only ACT- 18HS19 infection induced consistent transcription of IL-12 p35, a subunit of IL-12 p70.[iii] The standard product used in this kit is recombinant human IL-12 p70 with the molecular mass of 75 KDa.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Validation Images & Assay Conditions

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Gene/Protein Information For IL12A (Source: Uniprot.org, NCBI)

Alternative Names

CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL12 p70; IL-12 p70; IL-12 subunit p35; IL-12, subunit p35; interleukin 12, p35; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; natural killer cell stimulatory factor 1, 35 kD subunit; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; NKSF1; p35 IL12A CLMF, IL-12A, NFSK, NKSF1, P35 interleukin 12A interleukin-12 subunit alpha|CLMF p35|IL-12, subunit p35|IL35 subunit|NF cell stimulatory factor chain 1|NK cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|cytotoxic lymphocyte maturation factor 35 kDa subunit|interleukin 12, p35|interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)|interleukin-12 alpha chain

For more info on IL12A, check out the IL12A Infographic

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In this infographic, you will see the following information for IL12A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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