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Product Info Summary
| SKU: | A02261 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-IL-28B IFNL3 Antibody
View all IL-28B/IFN-lambda 3 Antibodies
SKU/Catalog Number
A02261
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-28B IFNL3 Antibody (Catalog # A02261). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
IL-28B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-IL-28B IFNL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02261)
Host
Rabbit
Contents
IL-28B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B. The immunogen is located within amino acids 120 - 170 of IL-28B .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.
Reactive Species
A02261 is reactive to IFNL3 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
21706 MW
Background of IL-28B/IFN-lambda 3
Interleukin 28 (IL-28B), also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1). The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2,3). All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02261 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-28B antibody can be used for detection of IL-28B by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL-28B in HeLa cell lysate with IL-28B antibody at (A) 1 and (B) 2 μg/ml.
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Immunofluorescence of IL-28B in HeLa cells with IL-28B antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IFNL3 (Source: Uniprot.org, NCBI)
Gene Name
IFNL3
Full Name
Interferon lambda-3
Weight
21706 MW
Superfamily
lambda interferon family
Alternative Names
IL28B, IL28C, IL-28B, IL28B, ZCYTO22, Interferon lambda-3, Cytokine Zcyto22, IFN-lambda-3 IFNL3 IFN-lambda-3, IFN-lambda-4, IL-28B, IL-28C, IL28B, IL28C interferon lambda 3 interferon lambda-3|cytokine Zcyto22|interferon, lambda 4|interleukin-28B|interleukin-28C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IFNL3, check out the IFNL3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IFNL3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-28B IFNL3 Antibody (A02261)
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