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Product Info Summary
| SKU: | A02824 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-IL-1RAcP IL1RAP Antibody
View all IL-1 RAcP/IL-1 R3 Antibodies
SKU/Catalog Number
A02824
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-1RAcP IL1RAP Antibody (Catalog # A02824). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
IL-1RAcP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-IL-1RAcP IL1RAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02824)
Host
Rabbit
Contents
IL-1RAcP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IL-1RAcP antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. The immunogen is located within the last 50 amino acids of IL-1RAcP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.
Reactive Species
A02824 is reactive to IL1RAP in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
65418 MW
Background of IL-1 RAcP/IL-1 R3
The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κB inducing kinae (NIK) and of NF-κB, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02824 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-1RAcP antibody can be used for detection of IL-1RAcP by Western blot at 1 μg/mL. Antibody can also be used for Immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL-1RAcP in HeLa whole cell lysate with IL-1RAcP antibody at 1 μg/mL.
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Immunocystochemistry of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 2 μg/ml.
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Immunofluorescence of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 5 μg/mL.
Red: IL-1RAcP Antibody (A02824)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For IL1RAP (Source: Uniprot.org, NCBI)
Gene Name
IL1RAP
Full Name
Interleukin-1 receptor accessory protein
Weight
65418 MW
Superfamily
interleukin-1 receptor family
Alternative Names
IL1R3, C3orf13, IL-1RAcP, IL1R3, Interleukin-1 receptor accessory protein, Interleukin-1 receptor 3, IL-1 receptor accessory protein IL1RAP C3orf13, IL-1RAcP, IL1R3 interleukin 1 receptor accessory protein interleukin-1 receptor accessory protein|IL-1 receptor accessory protein|interleukin-1 receptor 3|interleukin-1 receptor accessory protein beta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL1RAP, check out the IL1RAP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL1RAP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-1RAcP IL1RAP Antibody (A02824)
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