Anti-IFIT2 Antibody

SKU A04428
Size 100 μg
Reactivity Human
Clonality Polyclonal
Host Rabbit
Ig Isotype N/A
Applications WB

Overview

Product Name Anti-IFIT2 Antibody
SKU/Catalog Number A04428
Storage & Handling Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Size 100 μg
Description Rabbit IgG Polyclonal antibody for IFIT2 detection. Tested with WB in Human.
Cite This Product Anti-IFIT2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04428)
Host Rabbit
Contents/Buffer 100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Form Liquid
Immunogen A partial length recombinant IFIT2 protein (amino acids 150-370).
Reactivity Human

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Western blot analysis, 2-4 μg/ml

Images And Assay Conditions

Western blot analysis of IFIT2. Anti-IFIT2 antibody was used at 4 μg/ml on Hela lysate.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P09913
Gene Name IFIT2
Protein Name Interferon-induced protein with tetratricopeptide repeats 2
Alternative Names Interferon-induced protein with tetratricopeptide repeats 2;IFIT-2;ISG-54 K;Interferon-induced 54 kDa protein;IFI-54K;P54;IFIT2;CIG-42, G10P2, IFI54, ISG54;
Subcellular Localization Cytoplasm . Endoplasmic reticulum .
Molecular Weight 54632 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O- methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. .
Research Areas Human

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In stock
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A04428
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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