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Product Info Summary
| SKU: | M00642-Dyl488 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12)
SKU/Catalog Number
M00642-Dyl488
Size
100 μg/vial
Form
Liquid
Description
Boster Bio Anti-Human MVP DyLight® 488 conjugated Antibody (monoclonal, 8B12) catalog # M00642-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00642-Dyl488)
Host
Mouse
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN6.
Clonality
Monoclonal
Clone Number
8B12
Isotype
Mouse IgG2a
Immunogen
E. coli-derived human MVP recombinant protein (Position: A2-H259).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
M00642-Dyl488 is reactive to MVP in Human
Reconstitution
Observed Molecular Weight
39 kDa
Calculated molecular weight
99.327kDa
Background of MVP
Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00642-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (Fixed), 1-3μg/1x106 cells, human
Validation Images & Assay Conditions
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Boster Kit Box
Protein Target Info & Infographic
Gene/Protein Information For MVP (Source: Uniprot.org, NCBI)
Gene Name
MVP
Full Name
Major vault protein
Weight
99.327kDa
Alternative Names
Major vault protein; MVP; Lung resistance-related protein; MVP; LRP MVP LRP, VAULT1 major vault protein major vault protein|lung resistance-related protein|testicular secretory protein Li 30
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MVP, check out the MVP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MVP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12) (M00642-Dyl488)
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No publications found for M00642-Dyl488
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Customer Q&As
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1 Customer Q&As for Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12)
Question
We are currently using anti-Human MVP DyLight® 488 conjugated antibody(monoclonal, 8B12) M00642-Dyl488 for human tissue, and we are content with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on feline tissues as well?
Verified Customer
Verified customer
Asked: 2019-06-05
Answer
The anti-Human MVP DyLight® 488 conjugated antibody(monoclonal, 8B12) (M00642-Dyl488) has not been validated for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-06-05
