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Product Info Summary
| SKU: | FC00568-Biotin |
|---|---|
| Size: | 100ug |
| Reactive Species: | Cynomolgus monkey, Human, Baboon, Rhesus monkey |
| Host: | Mouse |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-human HLA-DR HLA-DRA Monoclonal Antibody Biotin Conjugated, Flow Validated
SKU/Catalog Number
FC00568-Biotin
Size
100ug
Form
Liquid
Description
Boster Bio Anti-human HLA-DR HLA-DRA Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00568-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human, Rhesus monkey, Cynomolgus monkey, Baboon.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-human HLA-DR HLA-DRA Monoclonal Antibody Biotin Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC00568-Biotin)
Host
Mouse
Contents
PBS pH 7.2, 0.09% sodium azide
Clonality
Monoclonal
Clone Number
Clone: L243
Isotype
IgG2a,k
Immunogen
Human B lymphocytes
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC00568-Biotin is reactive to HLA-DRA in Cynomolgus monkey, Human, Baboon, Rhesus monkey
Reconstitution
Calculated molecular weight
28607 MW
Background of HLA-DRA
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
FC00568-Biotin is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
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Monocytes gated PBMCs stained with biotin conjugated anti-human HLA-DR (clone L243) followed by SA-PE (red histogram). Monocytes gated PBMCs stained with biotin conjugated mouse IgG2a isotype control followed by SA-PE is shown in Blue histogram.
Protein Target Info & Infographic
Gene/Protein Information For HLA-DRA (Source: Uniprot.org, NCBI)
Gene Name
HLA-DRA
Full Name
HLA class II histocompatibility antigen, DR alpha chain
Weight
28607 MW
Superfamily
MHC class II family
Alternative Names
HLA class II histocompatibility antigen, DR alpha chain;MHC class II antigen DRA;HLA-DRA;HLA-DRA1; HLA-DRA HLA-DRA1 major histocompatibility complex, class II, DR alpha HLA class II histocompatibility , DR alpha chain|MHC class II DRA|histocompatibility HLA-DR alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on HLA-DRA, check out the HLA-DRA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for HLA-DRA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-human HLA-DR HLA-DRA Monoclonal Antibody Biotin Conjugated, Flow Validated (FC00568-Biotin)
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