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Product Info Summary
| SKU: | FC01508-PE-Cy7 |
|---|---|
| Size: | 100 tests, 200 tests |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human CD33 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated
View all Siglec-3/CD33 Antibodies
SKU/Catalog Number
FC01508-PE-Cy7
Size
100 tests, 200 tests
Form
Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA
Description
Boster Bio Anti-Human CD33 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Catalog# FC01508-PE-Cy7). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Human CD33 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC01508-PE-Cy7)
Host
Mouse
Contents
PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Clonality
Monoclonal
Clone Number
Clone: WM53
Isotype
IgG1,k
Immunogen
Human AML cells
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC01508-PE-Cy7 is reactive to CD33 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
39825 MW
Background of Siglec-3/CD33
The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3 (formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta, epsilon, and zeta. The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
FC01508-PE-Cy7 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
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Monocytes gated human PBMCs stained with mouse anti-human CD33 PE-Cyanine7 (clone WM53, red histogram). Blue histogram is for the monocytes gated PBMCs stained with IgG1 (MOPC31C) PE-Cyanine7 conjugated isotype control.
Protein Target Info & Infographic
Gene/Protein Information For CD33 (Source: Uniprot.org, NCBI)
Gene Name
CD33
Full Name
Myeloid cell surface antigen CD33
Weight
39825 MW
Superfamily
immunoglobulin superfamily
Alternative Names
Myeloid cell surface antigen CD33;Sialic acid-binding Ig-like lectin 3;Siglec-3;gp67;CD33;CD33;SIGLEC3; CD33 SIGLEC-3, SIGLEC3, p67 CD33 molecule myeloid cell surface CD33|CD33 (gp67)|CD33 molecule transcript|gp67|sialic acid-binding Ig-like lectin 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD33, check out the CD33 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD33: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human CD33 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (FC01508-PE-Cy7)
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