CD33 Antibodies

AND CD33 ELISA kits, CD33 Proteins

Many biological assays use antibodies to detect CD33, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD33 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD33 antibodies...

We validate the specificity of these antibodies to CD33 by testing them on tissues known to express CD33 positively and negatively. Browse below to find the CD33 antibody that suites your experiment. We have 15 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD33 Infographic by Boster Bio

All CD33 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CD33 Antibody Picoband®

16 Q&As

Human

Flow Cytometry, IHC, ICC, WB

$370
Cat # PB9932
100 μg/vial

Anti-CD33 Antibody Picoband®

15 Q&As

Mouse

IHC, WB

$370
Cat # RP1105
100 μg/vial

Anti-human CD33/Siglec 3 Monoclonal Antibody APC Conjugated, Flow Validated

Human

Flow Cytometry

$325
Cat # FC01508-APC
100 tests, 200 tests

Anti-human CD33/Siglec 3 Monoclonal Antibody Biotin Conjugated, Flow Validated

10 Q&As

Human

Flow Cytometry

$215
Cat # FC01508-Biotin
100ug

Anti-human CD33/Siglec 3 Monoclonal Antibody FITC Conjugated, Flow Validated

Human

Flow Cytometry

$235
Cat # FC01508-FITC
100 tests, 200 tests

Anti-human CD33/Siglec 3 Monoclonal Antibody PE Conjugated, Flow Validated

10 Q&As

Human

Flow Cytometry

$299
Cat # FC01508-PE
100 tests, 200 tests

Anti-human CD33/Siglec 3 Monoclonal Antibody Unconjugated, Flow Validated

2 Q&As

Human

Flow Cytometry

$152
Cat # FC01508
100ug, 500ug

Anti-CD33 Monoclonal Antibody

16 Q&As

Human

IP, WB

$370
Cat # M01508
100 μl

Anti-Human CD33 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

Human

Flow Cytometry

$363
Cat # FC01508-PE-Cy7
100 tests, 200 tests

Anti-CD33 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A01508
0.1 mg

Anti-Hu CD33 Purified Monoclonal Antibody

Human, Primate

Flow Cytometry, IP, IHC-F, ICC, WB, CyTOF

$299
Cat # M01508-1
0.1 mg

Anti-CD33 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01508-1
100ul

Human CD33 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP20138
Starting from 10ug

CD33 (NM_001772) Human Over-expression Lysate

Human

$628
Cat # LS000945
100 µg

Anti-Siglec-3/CD33 Reference Antibody (Gemtuzumab)

Human

ELISA, Flow Cytometry, FTA

$349
Cat # M01508-3
100 μg

CD33 Overview

Facts about Myeloid cell surface antigen CD33.

CD33 3D structure. Source: alphafold

Myeloid cell surface antigen CD33 (CD33)

Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (PubMed:10611343, PubMed:15597323, PubMed:11320212). Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked sialic acid- bearing glycans (PubMed:7718872).

Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine- based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK (PubMed:28325905, PubMed:10887109). These phosphorylations provide docking sites for the recruitment and activation of protein- tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:10556798, PubMed:10206955, PubMed:10887109).

Gene Information

Human
Gene Name:	CD33
Uniprot:	P20138
Entrez:	945

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD33 antigen (gp67); CD33 antigen; CD33 molecule; CD33; FLJ00391; gp67; myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; Sialic acid-binding Ig-like lectin 3; Siglec3; Siglec-3; SIGLEC3gp67

Molecular Weight

Mass (kDA):
39.825 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (51211054..51240016)

Tissue Specificity

Monocytic/myeloid lineage cells. In the brain, CD33 is mainly expressed on microglial cells.

Subcellular Localizations

[Isoform CD33M]: Cell membrane; Single-pass type I membrane protein.; [Isoform CD33m]: Peroxisome. CD33m isoform does not localize to cell surfaces but instead accumulates in peroxisomes.