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Product Info Summary
| SKU: | FC02184-Biotin |
|---|---|
| Size: | 100ug |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-human CD235a GYPA Monoclonal Antibody Biotin Conjugated, Flow Validated
View all Glycophorin A Antibodies
SKU/Catalog Number
FC02184-Biotin
Size
100ug
Form
Liquid
Description
Boster Bio Anti-human CD235a GYPA Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC02184-Biotin). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-human CD235a GYPA Monoclonal Antibody Biotin Conjugated, Flow Validated (Boster Biological Technology, Pleasanton CA, USA, Catalog # FC02184-Biotin)
Host
Mouse
Contents
PBS pH 7.2, 0.09% sodium azide
Clonality
Monoclonal
Clone Number
Clone: GYPA280
Isotype
IgG1,k
Immunogen
Recombinant human glycophorin A protein
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
FC02184-Biotin is reactive to GYPA in Human
Reconstitution
Calculated molecular weight
16331 MW
Background of Glycophorin A
Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also recently been designated CD235a (cluster of differentiation 235a). Glycophorins A (GYPA; this protein) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
FC02184-Biotin is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
User needs to optimize the dilution ratio for this antibody.
Validation Images & Assay Conditions
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RBCs gated human blood stained with biotin conjugated mouse anti-human CD235a (clone GYPA/280) followed by staining with SA-PE (red histogram). Blue histogram is for the RBCs gated stained whole blood stained with biotin conjugated mouse IgG1 (MOPC31) isotype control followed by staining with SAPE.
Protein Target Info & Infographic
Gene/Protein Information For GYPA (Source: Uniprot.org, NCBI)
Gene Name
GYPA
Full Name
Glycophorin-A
Weight
16331 MW
Superfamily
glycophorin A family
Alternative Names
Glycophorin-A;MN sialoglycoprotein;PAS-2;Sialoglycoprotein alpha;CD235a;GYPA;GPA; GYPA CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 glycophorin A (MNS blood group) glycophorin-A|MN sialoglycoprotein|Mi.V glycoprotein (24 AA)|erythroid-lineage-specific membrane sialoglycoprotein|glycophorin A (MN blood group)|glycophorin A, GPA|glycophorin Erik|glycophorin MiI|glycophorin MiV|glycophorin SAT|glycophorin Sta type C|recombinant glycophorin A-B Miltenberger-DR|sialoglycoprotein alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GYPA, check out the GYPA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GYPA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-human CD235a GYPA Monoclonal Antibody Biotin Conjugated, Flow Validated (FC02184-Biotin)
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