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- Table of Contents
2 Citations 7 Q&As
4 Citations
2 Citations
2 Citations 3 Q&As
Facts about Basigin.
Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans.
Human | |
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Gene Name: | BSG |
Uniprot: | P35613 |
Entrez: | 682 |
Belongs to: |
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No superfamily |
5F7; basigin (Ok blood group); Basigin; BSG; CD147 antigen; CD147; Collagenase stimulatory factor; EMMPRIN; EMMPRINTCSF; Extracellular matrix metalloproteinase inducer; Leukocyte activation antigen M6; M6; OK blood group antigen; OK; Tumor cell-derived collagenase stimulatory factor
Mass (kDA):
42.2 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (571283..583493) |
Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Cell membrane; Single-pass type I membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In spermatozoa, localized on the principal piece of caput and in the middle piece during transit in the corpus and cauda epididymides (By similarity).
PMID: 1634773 by Kasinrerk W., et al. Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule.
PMID: 1783610 by Miyauchi T., et al. The basigin group of the immunoglobulin superfamily: complete conservation of a segment in and around transmembrane domains of human and mouse basigin and chicken HT7 antigen.
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