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Product Info Summary
| SKU: | A05887-Dyl488 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human BMP5 DyLight® 488 conjugated Antibody
SKU/Catalog Number
A05887-Dyl488
Size
100 μg/vial
Form
Liquid
Description
Boster Bio Anti-Human BMP5 DyLight® 488 conjugated Antibody catalog # A05887-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human BMP5 DyLight® 488 conjugated Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05887-Dyl488)
Host
Rabbit
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human BMP5, different from the related mouse sequence by three amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
A05887-Dyl488 is reactive to BMP5 in Human
Reconstitution
Observed Molecular Weight
39 kDa
Calculated molecular weight
51.737kDa
Background of BMP-5
Bone morphogenetic protein 5 is a protein that in humans is encoded by the BMP5 gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05887-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (Fixed), 1-3μg/1x106 cells
Positive Control
FCM: U20S cell
Validation Images & Assay Conditions
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1. Flow Cytometry analysis of U20S cells using anti-Human BMP5 antibody (A05887-Dyl488).
Overlay histogram showing U20S cells stained with A05887-Dyl488 (Blue line). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabilized with permeabilization buffer. The cells were blocked with 10% normal goat serum. And then incubated with rabbit anti-Human BMP5 Antibody (A05887-Dyl488,1μg/1x106 cells) for 30 min at 20°C. Isotype control antibody (Green line) was rabbit IgG (1μg/1x106) used under the same conditions. Unlabelled sample (Red line) was also used as a control.
Protein Target Info & Infographic
Gene/Protein Information For BMP5 (Source: Uniprot.org, NCBI)
Gene Name
BMP5
Full Name
Bone morphogenetic protein 5
Weight
51.737kDa
Superfamily
TGF-beta family
Alternative Names
Bone morphogenetic protein 5; BMP-5; BMP5 BMP5 bone morphogenetic protein 5 bone morphogenetic protein 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BMP5, check out the BMP5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BMP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human BMP5 DyLight® 488 conjugated Antibody (A05887-Dyl488)
Hello CJ!
A05887-Dyl488 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Wang Q, Xue Ml, Zhao Gq, Liu Mg, Ma Yn, Ma Y. Int J Ophthalmol. 2015 Feb 18;8(1):39-45. Doi: 10.3980/J.Issn.2222-3959.2015.01.07. Ecollection 2015. Form-Deprivation Myopia Induces Decreased Expression Of Bone Morphogenetic Protein-2, 5 In Guinea P...
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