Anti-Hu CD305 Purified LAIR1 Monoclonal Antibody

Product Name

Anti-Hu CD305 Purified LAIR1 Monoclonal Antibody

View all LAIR1 Antibodies

SKU/Catalog Number

M03470

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD305 Purified LAIR1 Monoclonal Antibody (Catalog# M03470). Tested in Flow Cytometry, IP, WB application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD305 Purified LAIR1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03470)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

NKTA255

Isotype

Mouse IgG1

Immunogen

Activated NK cells and CD3- thymocytes. The mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M03470 is reactive to LAIR1 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

31412 MW

Background of LAIR1

CD305, also known as LAIR1 (leukocyte-associated Ig-like receptor 1), is an inhibitory receptor found on many types of peripheral blood cells. It serves to suppress cell cytotoxicity, activation, proliferation, and differentiation regarding autoantigens via its two intracellular ITIM sites. CD305 belongs to the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family of proteins. It reacts with collagen ligands.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M03470 is guaranteed for Flow Cytometry, IP, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For LAIR1 (Source: Uniprot.org, NCBI)

Alternative Names

LAIR1 LAIR1 CD305, LAIR-1 leukocyte associated immunoglobulin like receptor 1 leukocyte-associated immunoglobulin-like receptor 1|immunoglobulin heavy chain variable region|leukocyte-associated Ig-like receptor 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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