LAIR1 Antibodies

AND LAIR1 ELISA kits, LAIR1 Proteins

Many biological assays use antibodies to detect LAIR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LAIR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LAIR1 antibodies...

We validate the specificity of these antibodies to LAIR1 by testing them on tissues known to express LAIR1 positively and negatively. Browse below to find the LAIR1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LAIR1 Infographic by Boster Bio

All LAIR1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Hu CD305 Purified LAIR1 Monoclonal Antibody

Human

Flow Cytometry, IP, WB

$299
Cat # M03470
0.1 mg

Anti-CD305 LAIR1 Antibody

Human

ELISA, WB

$380
Cat # A03470
100ul

LAIR1 (NM_002287) Human Recombinant Protein

$1062
Cat # PROTQ6GTX8
20 µg

Mouse LAIR1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ8BG84
Starting from 10ug

Human LAIR1 ELISA Kit PicoKine®

8 Q&As

Human

ELISA

$499
Cat # EK2111
96 wells/kit, with removable strips.

LAIR1 (NM_002287) Human Over-expression Lysate

Human

$628
Cat # LS003903
100 µg

Anti-LAIR1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A03470-2
100 µg/vial

LAIR1 Overview

Facts about Leukocyte-associated immunoglobulin-like receptor 1.

LAIR1 3D structure. Source: alphafold

Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1)

Acts as an inhibitory receptor that plays a constitutive negative regulatory function in cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11.

It also reduces the growth of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases.

Gene Information

Human
Gene Name:	LAIR1
Uniprot:	Q6GTX8
Entrez:	3903

Family

Belongs to:

No superfamily

Alternative Names

CD305 antigen; CD305; CD305leukocyte-associated Ig-like receptor 1; HLAIR1; LAIR1; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1

Molecular Weight

Mass (kDA):
31.412 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54351384..54370556, complement)

Tissue Specificity

Expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells. Highly expressed in naive T-cells and B-cells but no expression on germinal center B-cells. Abnormally low expression in naive B-cells from HIV-1 infected patients. Very low expression in NK cells from a patient with chronic active Epstein-Barr virus infection.