Anti-Hu CD178 Purified FASLG Monoclonal Antibody

Product Name

Anti-Hu CD178 Purified FASLG Monoclonal Antibody

View all Fas Ligand/TNFSF6 Antibodies

SKU/Catalog Number

M00925-2

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD178 Purified FASLG Monoclonal Antibody (Catalog# M00925-2). Tested in Flow Cytometry, IP, WB, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD178 Purified FASLG Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00925-2)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

NOK-1

Isotype

Mouse IgG1

Immunogen

L5178Y mouse T lymphoma cells expressing recombinant human CD178. The mouse monoclonal antibody NOK-1 recognizes an extracellular epitope of CD178 / Fas-L, an approximately 40 kDa transmembrane glycoprotein expressed on neutrophils, monocytes, and activated T and NK cells.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00925-2 is reactive to FASLG in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

31485 MW

Background of Fas Ligand/TNFSF6

CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

M00925-2 is guaranteed for Flow Cytometry, IP, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 µg/ml

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For FASLG (Source: Uniprot.org, NCBI)

Alternative Names

APTL, FASL, FAS-ligand, CD95L, TNFSF6, TNLG1A FASLG ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A Fas ligand tumor necrosis factor ligand superfamily member 6|CD95 ligand|Fas ligand (TNF superfamily, member 6)|apoptosis (APO-1) ligand 1|apoptosis ligand|fas ligand|mutant tumor necrosis factor family member 6|tumor necrosis factor ligand 1A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis