Product Info Summary
SKU: | A05044-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Hepassocin FGL1 Antibody
View all Hepassocin/FGL1 Antibodies
SKU/Catalog Number
A05044-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Hepassocin FGL1 Antibody catalog # A05044-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Hepassocin FGL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05044-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Hepassocin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05044-1 is reactive to FGL1 in Human, Mouse, Rat
Applications
A05044-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
36379 MW
Background of Hepassocin/FGL1
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20.
Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31.
Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
Validation Images & Assay Conditions
![a05044 1 anti hepassocin fgl1 antibody ihc testing 2 a05044 1 anti hepassocin fgl1 antibody ihc testing 2](https://www.bosterbio.com/media/catalog/product/a/0/a05044-1-anti-hepassocin-fgl1-antibody-ihc-testing-2.jpg)
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Figure 2. Immunohistochemistry validation of FGL1 using Anti-Hepassocin FGL1 Antibody (A05044-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Rat liver![a05044 1 anti hepassocin fgl1 antibody ihc testing 3 a05044 1 anti hepassocin fgl1 antibody ihc testing 3](https://www.bosterbio.com/media/catalog/product/a/0/a05044-1-anti-hepassocin-fgl1-antibody-ihc-testing-3.jpg)
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Figure 3. Immunohistochemistry validation of FGL1 using Anti-Hepassocin FGL1 Antibody (A05044-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Liver![a05044 1 anti hepassocin fgl1 antibody ihc testing 4 a05044 1 anti hepassocin fgl1 antibody ihc testing 4](https://www.bosterbio.com/media/catalog/product/a/0/a05044-1-anti-hepassocin-fgl1-antibody-ihc-testing-4.jpg)
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Figure 4. Immunohistochemistry validation of FGL1 using Anti-Hepassocin FGL1 Antibody (A05044-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Liver![a05044 1 anti hepassocin fgl1 antibody wb testing 1 a05044 1 anti hepassocin fgl1 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a05044-1-anti-hepassocin-fgl1-antibody-wb-testing-1.jpg)
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Figure 1. Western blotting validation for Anti-Hepassocin FGL1 Antibody A05044-1
Western Blot (WB) analysis of Mouse Liver cells using Hepassocin polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For FGL1 (Source: Uniprot.org, NCBI)
Gene Name
FGL1
Full Name
Fibrinogen-like protein 1
Weight
36379 MW
Alternative Names
FGL1; fibrinogen-like 1; fibrinogen-like protein 1; Fibrinogen-like-protein 1; FREP1; Hepassocin; hepatocellular carcinoma-related sequence; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HFREP1MGC12455; HP-041; LFIRE1; LFIRE-1; Liver fibrinogen-related protein 1 FGL1 HFREP1, HP-041, HPS, LFIRE-1, LFIRE1 fibrinogen like 1 fibrinogen-like protein 1|hepassocin|hepatocellular carcinoma-related sequence|hepatocyte-derived fibrinogen-related protein 1|liver fibrinogen-related protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FGL1, check out the FGL1 Infographic
![FGL1 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FGL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hepassocin FGL1 Antibody (A05044-1)
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