Anti-HEPACAM family member 2 HEPACAM2 Antibody

Product Name

Anti-HEPACAM family member 2 HEPACAM2 Antibody

View all Hepacam2 Antibodies

SKU/Catalog Number

A12313

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-HEPACAM family member 2 HEPACAM2 Antibody (Catalog # A12313). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

HEPACAM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-HEPACAM family member 2 HEPACAM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12313)

Host

Rabbit

Contents

HEPACAM2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Rabbit polyclonal HEPACAM2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HEPACAM2. The immunogen is located within amino acids 370 - 420 of HEPACAM2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

HEPACAM2 antibody is human, mouse and rat reactive. At least two isoforms of HEPACAM2 are known to exist; this antibody will detect both isoforms. HEPACAM2 antibody is predicted to not cross-react with HEPACAM.

Reactive Species

A12313 is reactive to HEPACAM2 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

51407 MW

Background of Hepacam2

HEPACAM2 (Hepatocyte cell adhesion molecule 2), a type I N-linked transmembrane glycoprotein, belongs to the immunoglobulin superfamily. The exact function of HEPACAM2 is currently unknown, but the related protein HEPACAM forms cishomodimers on the cell surface to regulate the cell adhesion and may inhibit cell growth through suppression of cell proliferation. HEPACAM and HEPACAM2 mRNA are differentially regulated in canine tumors, with HEPACAM2 mRNA showing increased levels in adenomas, but decreased levels in metastatic carcinomas compared to normal tissues, while HEPACAM protein levels decreased in adenomas. It is therefore likely that HEPACAM2 plays a different role than HEPACAM in the development and progression to tumors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A12313 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

HEPACAM2 antibody can be used for detection of HEPACAM2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For HEPACAM2 (Source: Uniprot.org, NCBI)

Alternative Names

MIKI, MIKI, UNQ305/PRO346, HEPACAM family member 2, Mitotic kinetics regulator

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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