Click image to see more details
Product Info Summary
| SKU: | M00739-1 |
|---|---|
| Size: | 100ug/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | IHC |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody
View all CGA (HCG-alpha) & CGB (HCG-beta) Antibodies
SKU/Catalog Number
M00739-1
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody (Catalog # M00739-1). Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00739-1)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: HCGab/52
Isotype
IgG1, kappa
Immunogen
Purified hCG protein
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M00739-1 is reactive to CGA (HCG-alpha) & CGB (HCG-beta) in Human
Reconstitution
Reconstitute with distilled water.
Calculated molecular weight
13075 MW
Background of CGA (HCG-alpha) & CGB (HCG-beta)
This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00739-1 is guaranteed for IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
Click image to see more details
Formalin-fixed, paraffin-embedded human Placenta stained with Anti-hCG Mouse Monoclonal Antibody (HCGab/52)
Protein Target Info & Infographic
Gene/Protein Information For CGA (HCG-alpha) & CGB (HCG-beta) (Source: Uniprot.org, NCBI)
Gene Name
CGA (HCG-alpha) & CGB (HCG-beta)
Full Name
Weight
13075 MW
Alternative Names
Glycoprotein hormones alpha chain;Anterior pituitary glycoprotein hormones common subunit alpha;Choriogonadotropin alpha chain;Chorionic gonadotrophin subunit alpha;CG-alpha;Follicle-stimulating hormone alpha chain;FSH-alpha;Follitropin alpha chain;Luteinizing hormone alpha chain;LSH-alpha;Lutropin alpha chain;Thyroid-stimulating hormone alpha chain;TSH-alpha;Thyrotropin alpha chain;CGA;
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CGA (HCG-alpha) & CGB (HCG-beta), check out the CGA (HCG-alpha) & CGB (HCG-beta) Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CGA (HCG-alpha) & CGB (HCG-beta): database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody (M00739-1)
Hello CJ!
No publications found for M00739-1
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-HCG Holo (Pregnancy & Choriocarcinoma Marker) Monoclonal Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
