Anti-Hax1a Monoclonal Antibody [8F9G7]

Product Name

Anti-Hax1a Monoclonal Antibody [8F9G7]

View all HAX-1 Antibodies

SKU/Catalog Number

M01495

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hax1a Monoclonal Antibody [8F9G7] (Catalog # M01495). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Hax1a monoclonal antibody can be stored at -20°C, stable for one year.

Cite This Product

Anti-Hax1a Monoclonal Antibody [8F9G7] (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01495)

Host

Mouse

Contents

Hax1a Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

Clone: 8F9G7

Isotype

IgG1,k

Immunogen

Mouse monoclonal Hax1a antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

beta-Actin antibody is human, mouse, rat, rabbit, chicken, zebrafish and drosophila reactive.

Reactive Species

M01495 is reactive to HAX1 in Human, Mouse, Rat

Applications

M01495 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

31621 MW

Background of HAX-1

The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Hax1a antibody can be used for detection of Hax1A by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of Hax1a in human brain tissue lysate with Hax1a antibody at (A) 1 and (B) 2 μg/mL.

Gene/Protein Information For HAX1 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ17042; FLJ93803; HAX1; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1 associated protein X-1; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HS1BP1FLJ18492; HSP1BP-1; SCN3 HAX1 HCLSBP1, HS1BP1, SCN3 HCLS1 associated protein X-1 HCLS1-associated protein X-1|HAX-1|HCLS1 (and PKD2) associated protein|HS1 binding protein|HS1-associating protein X-1|HS1-binding protein 1|HSP1BP-1

For more info on HAX1, check out the HAX1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HAX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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