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Product Info Summary
| SKU: | A13012 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Guanylate-binding protein 6 GBP6 Antibody
SKU/Catalog Number
A13012
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Guanylate-binding protein 6 GBP6 Antibody (Catalog # A13012). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
GBP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Guanylate-binding protein 6 GBP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13012)
Host
Rabbit
Contents
GBP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
GBP6 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human GBP6. The immunogen is located within the last 50 amino acids of GBP6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GBP6 antibody is predicted to not cross-react with other GBP family members.
Reactive Species
A13012 is reactive to GBP6 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
72427 MW
Background of GBP6
The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13012 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GBP6 antibody can be used for detection of GBP6 by Western blot at 0.5 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GBP6 in Hela cell lysate with GBP6 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of GBP6 in HeLa cells with GBP6 antibody at 2.5 μg/mL.
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Immunofluorescence of GBP6 in HeLa cells with GBP6 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For GBP6 (Source: Uniprot.org, NCBI)
Gene Name
GBP6
Full Name
Guanylate-binding protein 6
Weight
72427 MW
Superfamily
TRAFAC class dynamin-like GTPase superfamily
Alternative Names
Guanylate-binding protein 6, GTP-binding protein 6, GBP-6 GBP6 guanylate binding protein family member 6 guanylate-binding protein 6|GBP-6|GTP-binding protein 6|guanine nucleotide-binding protein 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GBP6, check out the GBP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GBP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Guanylate-binding protein 6 GBP6 Antibody (A13012)
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