Anti-Glucagon Antibody (Monoclonal, K79bB10)

SKU MA1047
Size 100μg/vial
Reactivity Human, Mouse, Rabbit, Rat
Clonality Monoclonal
Clone Number K79bB10
Host Mouse
Ig Isotype Mouse IgG1
Applications IHC

Overview

Product Name Anti-Glucagon Antibody (Monoclonal, K79bB10)
SKU/Catalog Number MA1047
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100μg/vial
Description Mouse IgG monoclonal antibody for Glucagon, glucagon (GCG) detection. Tested with IHC-P in Human, mouse, rat, rabbit. No cross reactivity with other proteins.
Cite This Product Anti-Glucagon Antibody (Monoclonal, K79bB10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1047)
Host Mouse
Contents/Buffer Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Form Lyophilized
Immunogen Polymerized porcine glucagon.
Reactivity Human, Mouse, Rabbit, Rat

Assay Details

Assay Dilutions Overview

Concentration: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Human, mouse, rat, rabbit, By Heat

Boster's Secondary Antibodies And IHC, WB Kits

The following reagents are used to generate the images below.

Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Images And Assay Conditions

Anti-Glucagon antibody (monoclonal), MA1047, IHC(P)
IHC(P): Rat Pancreas Tissue

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P06883
Gene Name Gcg
Protein Name Glucagon
Tissue Specificity Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. .
Alternative Names Glucagon;Glicentin;Glicentin-related polypeptide;GRPP;Oxyntomodulin;OXM;OXY;Glucagon;Glucagon-like peptide 1;GLP-1;Glucagon-like peptide 1(7-37);GLP-1(7-37);Glucagon-like peptide 1(7-36);GLP-1(7-36);Glucagon-like peptide 2;GLP-2;Gcg;
Subcellular Localization Secreted.
Molecular Weight 20846 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. .
Research Areas Human, Mouse, Rabbit, Rat

*You can search these to find other products in these research areas.
Background Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. The human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.

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In stock
Order Product
MA1047
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$280.00

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Publications

The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus
Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System
Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil?lymphocyte ratio in rats with or without hidden diabetes mellitus
Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice
Chen Ll, Yang Wh, Zheng J, Hu X, Kong W, Zhang Hh. Nutr Metab (Lond). 2010 May 26;7:45. Doi: 10.1186/1743-7075-7-45. Effect Of Catch-Up Growth After Food Restriction On The Entero-Insular Axis In Rats.
Lan F, Yue X, Han L, Shi Z, Yang Y, Pu P, Yao Z, Kang C. Int J Oncol. 2012 Feb;40(2):519-26. Doi: 10.3892/Ijo.2011.1215. Epub 2011 Sep 28. Genome-Wide Identification Of Tcf7L2/Tcf4 Target Mirnas Reveals A Role For Mir-21 In Wnt-Driven Epithelial C...
Jiang H, Deng Xf, Duan Cm, Chen C, Xiang Jl, Lu Yl, Ma Qf. Lymphology. 2011 Mar;44(1):21-8. Somatostatin Receptors Sstr2 And Sstr5 Are Expressed In The Human Thoracic Duct.
Zhang Y, Ye C, Wang G, Gao Y, Tan K, Zhuo Z, Liu Z, Xia H, Yang D, Li P. Biomed Res Int. 2013;2013:526367. Doi: 10.1155/2013/526367. Epub 2013 May 27. Kidney-Targeted Transplantation Of Mesenchymal Stem Cells By Ultrasound-Targeted Microbubble Des...
Zhang W, Jin H, Hu Y, Yu Y, Li X, Ding Z, Kang Y, Wang B. Hum Gene Ther. 2010 Feb;21(2):171-8. Doi: 10.1089/Hum.2009.095. Protective Response Against Type 1 Diabetes In Nonobese Diabetic Mice After Coimmunization With Insulin And Dna Encoding Proi...
Liu Jj, Raynal S, Bailb?? D, Gausseres B, Carbonne C, Autier V, Movassat J, Kergoat M, Portha B. Biochim Biophys Acta. 2015 May;1852(5):980-91. Doi: 10.1016/J.Bbadis.2015.02.001. Epub 2015 Feb 9. Expression Of The Kynurenine Pathway Enzymes In The...
Tang Mm, Zhu Qe, Fan Wz, Zhang Sl, Li Dz, Liu Lz, Chen M, Zhang M, Zhou J, Wei Cj. Mol Ther. 2011 Jan;19(1):60-6. Doi: 10.1038/Mt.2010.187. Epub 2010 Sep 14. Intra-Arterial Targeted Islet-Specific Expression Of Sirt1 Protects ?? Cells From Strepto...

Customer Q&As

  • Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
    A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
  • Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
    A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact [email protected]
  • Q: Can you provide monoclonal antibodies carrier free?
    A: For most of our monoclonal antibodies, we are unable to provide them carrier free. If you would like to check if a specific antibody can be provided carrier free, please send an email to [email protected]
  • Q: What are some alternative names that could be used to describe this product?
    A: Some common names include but are not limited to glp 1 antibody, glp1 antibody, glp2 antibody
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