Product Info Summary
SKU: | A04681S123 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-GADD 45 Gamma (S123) GADD45G Antibody
SKU/Catalog Number
A04681S123
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GADD 45 Gamma (S123) GADD45G Antibody catalog # A04681S123. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GADD 45 Gamma (S123) GADD45G Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04681S123)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GADD 45gamma
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04681S123 is reactive to GADD45G in Human, Mouse, Rat
Applications
A04681S123 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
17121 MW
Background of GADD45G
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Chu W., J. Biol. Chem. 270:10236-10245(1995).
Park J.-H., Cancer Res. 65:2804-2814(2005).
Deloukas P., Nature 429:375-381(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
![a04681s123 anti gadd 45 gamma s123 gadd45g antibody ihc testing 1 a04681s123 anti gadd 45 gamma s123 gadd45g antibody ihc testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a04681s123-anti-gadd-45-gamma-s123-gadd45g-antibody-ihc-testing-1.jpg)
Click image to see more details
Figure 1. Immunohistochemistry validation of GADD45G using Anti-GADD 45 Gamma (S123) GADD45G Antibody (A04681S123).
Immunohistochemistry (IHC) analyzes of GADD 45γ (S123) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For GADD45G (Source: Uniprot.org, NCBI)
Gene Name
GADD45G
Full Name
Growth arrest and DNA damage-inducible protein GADD45 gamma
Weight
17121 MW
Superfamily
GADD45 family
Alternative Names
CR6DNA damage-inducible transcript 2 protein; Cytokine-responsive protein CR6; DDIT-2; DDIT2GADD45-gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible, gamma; GRP1717 kD GADD45G CR6, DDIT2, GADD45gamma, GRP17 growth arrest and DNA damage inducible gamma growth arrest and DNA damage-inducible protein GADD45 gamma|DDIT-2|DNA damage-inducible transcript 2 protein|GADD45-gamma|cytokine-responsive protein CR6|gadd-related protein, 17 kD
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GADD45G, check out the GADD45G Infographic
![GADD45G infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GADD45G: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GADD 45 Gamma (S123) GADD45G Antibody (A04681S123)
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