Anti-Phospho-GABAB R1 (Ser923) Antibody

Product Name

Anti-Phospho-GABAB R1 (Ser923) Antibody

View all GABA-B R1 Antibodies

SKU/Catalog Number

P07297

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Phospho-GABAB R1 (Ser923) Antibody (Catalog # P07297). Tested in WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. After date of receipt, stable for at least 1 year at -20°C.

Cite This Product

Anti-Phospho-GABAB R1 (Ser923) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P07297)

Host

Rabbit

Contents

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser923 of the R1-subunit of rat GABAB receptor, conjugated to keyhole limpet hemocyanin (KLH). Immunogen species is Rat.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

P07297 is reactive to GABBR1 in Mouse, Rat

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Observed Molecular Weight

52 kDa

Calculated molecular weight

111534 MW

Background of GABA-B R1

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABA-A and the GABA-B subtype of receptors. GABA-B receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABA-B receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser-923 is thought to be important in the regulation of GABA-B receptor function.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

P07297 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For GABBR1 (Source: Uniprot.org, NCBI)

Alternative Names

dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, FLJ92613 antibody, GABA-B receptor 1 antibody, GABA-B-R1 antibody, GABA-BR1 antibody, GABAB R1 antibody, GABAB subunit 1c antibody, GABABR1 antibody, GABBR1 3 antibody, GABBR1 antibody, GABR1_HUMAN antibody, Gamma aminobutyric acid (GABA) B receptor 1 antibody, Gamma-aminobutyric acid type B receptor subunit 1 antibody, Gb1 antibody, GPRC3A antibody, Seven transmembrane helix receptor antibody GABBR1 GABABR1-3, GB1, GPRC3A, GABBR1 gamma-aminobutyric acid type B receptor subunit 1 gamma-aminobutyric acid type B receptor subunit 1|GABA-B receptor, R1 subunit|gamma-aminobutyric acid (GABA) B receptor, 1|seven transmembrane helix receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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