Product Info Summary
SKU: | A05523-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-FBXW11 Antibody
SKU/Catalog Number
A05523-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-FBXW11 Antibody catalog # A05523-1. Tested in WB,ICC/IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FBXW11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05523-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human Cytochrome P450 8B1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05523-1 is reactive to FBXW11 in Human
Applications
A05523-1 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
62091 MW
Background of FBXW11
Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Gaafvels M., Genomics 56:184-196(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Muzny D.M., Nature 440:1194-1198(2006)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For FBXW11 (Source: Uniprot.org, NCBI)
Gene Name
FBXW11
Full Name
F-box/WD repeat-containing protein 11
Weight
62091 MW
Alternative Names
beta-transducin repeat-containing protein 2; BTRC2F-box/WD repeat-containing protein 1B; BTRCP2FBW1B; F-box and WD repeat domain containing 11; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 11; Fbw11; FBXW1BFbw1b; Homologous to Slimb protein; Hos; KIAA0696F-box and WD repeats protein beta-TrCP2 FBXW11 BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, NEDJED F-box and WD repeat domain containing 11 F-box/WD repeat-containing protein 11|F-box and WD repeats protein beta-TrCP2|F-box and WD-40 domain protein 11|F-box and WD-40 domain protein 1B|F-box protein Fbw1b|F-box/WD repeat-containing protein 1B|beta-transducin repeat-containing protein 2|homologous to Slimb protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FBXW11, check out the FBXW11 Infographic
![FBXW11 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FBXW11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FBXW11 Antibody (A05523-1)
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No publications found for A05523-1
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