Anti-Factor XIIIa (Coagulation Factor XIIIA Chain) Monoclonal Antibody

Product Name

Anti-Factor XIIIa (Coagulation Factor XIIIA Chain) Monoclonal Antibody

View all Factor XIIIa Antibodies

SKU/Catalog Number

M02047

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-Factor XIIIa (Coagulation Factor XIIIA Chain) Monoclonal Antibody (Catalog # M02047). Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-Factor XIIIa (Coagulation Factor XIIIA Chain) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02047)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: F13A1/1683

Isotype

IgG2b, kappa

Immunogen

Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M02047 is reactive to F13A1 in Human

Applications

M02047 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

83267 MW

Background of Factor XIIIa

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. This monoclonal antibody recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconstitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

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Formalin-fixed, paraffin-embedded human Histiocytoma stained with Anti-Factor XIIIa Mouse Monoclonal Antibody (F13A1/1683).

Gene/Protein Information For F13A1 (Source: Uniprot.org, NCBI)

Alternative Names

bA525O21.1 (coagulation factor XIII, A1 polypeptide); coagulation factor XIII A chain; coagulation factor XIII, A1 polypeptide; Coagulation factor XIIIa; EC 2.3.2.13; F13A; F13A1; F13Acoagulation factor XIII, A polypeptide; factor XIIIa; fibrin stabilizing factor, A subunit; fibrinoligase; FSF, A Subunit; Protein-glutamine gamma-glutamyltransferase A chain; TGase; Transglutaminase A chain; transglutaminase. plasma F13A1 F13A coagulation factor XIII A chain coagulation factor XIII A chain|FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII, A polypeptide|coagulation factor XIII, A1 polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma

For more info on F13A1, check out the F13A1 Infographic

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In this infographic, you will see the following information for F13A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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