Product Info Summary
SKU: | A01067 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-ET-1 EDN1 Antibody
View all Endothelin-1 Antibodies
SKU/Catalog Number
A01067
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ET-1 EDN1 Antibody catalog # A01067. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ET-1 EDN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01067)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ET-1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01067 is reactive to EDN1 in Human
Applications
A01067 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
24425 MW
Background of Endothelin-1
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-P 100-300
WB 1:500-1:2000
ELISA 1:20000
Validation Images & Assay Conditions
![a01067 anti et 1 edn1 antibody wb testing 1 a01067 anti et 1 edn1 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a01067-anti-et-1-edn1-antibody-wb-testing-1.jpg)
Click image to see more details
Western blot analysis of mouse lung cells using ET-1 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000
![a01067 anti et 1 edn1 antibody wb testing 2_1 a01067 anti et 1 edn1 antibody wb testing 2_1](https://www.bosterbio.com/media/catalog/product/a/0/a01067-anti-et-1-edn1-antibody-wb-testing-2_1.jpg)
Click image to see more details
Western blot analysis of lysate from mouse lung, using EDN1 Antibody.
Protein Target Info & Infographic
Gene/Protein Information For EDN1 (Source: Uniprot.org, NCBI)
Gene Name
EDN1
Full Name
Endothelin-1
Weight
24425 MW
Superfamily
endothelin/sarafotoxin family
Alternative Names
ARCND3; EDN1; endothelin 1; Endothelin-1; ET1; HDLCQ7; PPET1; preproendothelin-1; QME EDN1 ARCND3, ET1, HDLCQ7, PPET1, QME endothelin 1 endothelin-1|preproendothelin-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EDN1, check out the EDN1 Infographic
![EDN1 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EDN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ET-1 EDN1 Antibody (A01067)
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No publications found for A01067
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