Anti-EGR2 Antibody Picoband®

Product Name

Anti-EGR2 Antibody Picoband®

View all EGR2 Antibodies

SKU/Catalog Number

PA2178

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-EGR2 Antibody catalog # PA2178. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EGR2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2178)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human EGR2, different from the related rat and mouse sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2178 is reactive to EGR2 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

53 kDa

Calculated molecular weight

50302 MW

Background of EGR2

Early growth response protein 2, also called EGR2 or E3 SUMO-protein ligase EGR2, is a protein that in humans is encoded by the EGR2 gene. This gene is mapped to 10q21.3. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PA2178 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Positive Control

WB: NIH3T3 Cell, MCF-7 Cell

Validation Images & Assay Conditions

Gene/Protein Information For EGR2 (Source: Uniprot.org, NCBI)

Alternative Names

E3 SUMO-protein ligase EGR2;6.3.2.-;AT591;Early growth response protein 2;EGR-2;Zinc finger protein Krox-20;EGR2;KROX20; EGR2 AT591, CHN1, CMT1D, CMT4E, KROX20 early growth response 2 E3 SUMO-protein ligase EGR2|E3 SUMO-protein transferase ERG2|KROX-20, Drosophila, homolog (early growth response-2)|early growth response protein 2|zinc finger protein Krox-20

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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