Anti-EGFL4 Antibody

Product Name

Anti-EGFL4 Antibody

View all MEGF8 Antibodies

SKU/Catalog Number

A12840

Size

100μl

Form

Liquid

Description

Boster Bio Anti-EGFL4 Antibody catalog # A12840. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EGFL4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12840)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human EGFL4. at AA rangle: 1220-1300

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12840 is reactive to MEGF8 in Human

Applications

A12840 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

303100 MW

Background of MEGF8

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using EGFL4 Polyclonal antibody.

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Western Blot (WB) analysis of specific cells using EGFL4 Polyclonal antibody.

Gene/Protein Information For MEGF8 (Source: Uniprot.org, NCBI)

Alternative Names

C19orf49; chromosome 19 open reading frame 49; EGFL4MGC120684; EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; Epidermal growth factor-like protein 4; FLJ22365; HBV pre-s2 binding protein 1; KIAA0817; MGC138147; multiple EGF-like domain protein 4; Multiple EGF-like domains protein 8; multiple EGF-like-domains 8; multiple epidermal growth factor-like domains 8; multiple epidermal growth factor-like domains protein 8; SBP1 MEGF8 C19orf49, CRPT2, EGFL4, SBP1 multiple EGF like domains 8 multiple epidermal growth factor-like domains protein 8|EGF-like domain-containing protein 4|EGF-like-domain, multiple 4|HBV pre-S2-binding protein 1|HBV pre-s2 binding protein 1|epidermal growth factor-like protein 4|hepatitis B virus pre-S2-binding protein 1

For more info on MEGF8, check out the MEGF8 Infographic

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In this infographic, you will see the following information for MEGF8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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