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Product Info Summary
| SKU: | A04348 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-DR6 TNFRSF21 Antibody
View all DR6/TNFRSF21 Antibodies
SKU/Catalog Number
A04348
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DR6 TNFRSF21 Antibody (Catalog # A04348). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
DR6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-DR6 TNFRSF21 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04348)
Host
Rabbit
Contents
DR6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
DR6 antibody was raised against a 15 amino acid peptide near the amino terminus of human DR6. The immunogen is located within amino acids 30 - 80 of DR6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.
Reactive Species
A04348 is reactive to TNFRSF21 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
71845 MW
Background of DR6/TNFRSF21
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04348 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DR6 antibody can be used for detection of DR6 by Western blot at 1:500 dilution. An approximately 68 kDa band can be detected.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DR6 in K562 (1
Protein Target Info & Infographic
Gene/Protein Information For TNFRSF21 (Source: Uniprot.org, NCBI)
Gene Name
TNFRSF21
Full Name
Tumor necrosis factor receptor superfamily member 21
Weight
71845 MW
Alternative Names
DR6, CD358, BM-018, DR6, UNQ437/PRO868, Tumor necrosis factor receptor superfamily member 21, Death receptor 6 TNFRSF21 BM-018, CD358, DR6 TNF receptor superfamily member 21 tumor necrosis factor receptor superfamily member 21|TNFR-related death receptor 6|death receptor 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNFRSF21, check out the TNFRSF21 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNFRSF21: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DR6 TNFRSF21 Antibody (A04348)
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