Anti-Dopamine Receptor D3/DRD3 Antibody Picoband®

Product Name

Anti-Dopamine Receptor D3/DRD3 Antibody Picoband®

View all Dopamine D3R/DRD3 Antibodies

SKU/Catalog Number

PA1584

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Dopamine Receptor D3/DRD3 Antibody catalog # PA1584. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Dopamine Receptor D3/DRD3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1584)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3, different from the related rat and mouse sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1584 is reactive to DRD3 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

42 kDa

Calculated molecular weight

44225 MW

Background of Dopamine D3R/DRD3

DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1584 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, Human, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Testis Tissue, Rat Brain Tissue, U87 Cell, HELA Cell
IHC: Rat Brain Tissue

Validation Images & Assay Conditions

Gene/Protein Information For DRD3 (Source: Uniprot.org, NCBI)

Alternative Names

D (3) dopamine receptor;Dopamine D3 receptor;DRD3; DRD3 D3DR, ETM1, FET1 dopamine receptor D3 D(3) dopamine receptor|essential tremor 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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