Click image to see more details
Product Info Summary
| SKU: | A02076-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-DNA endonuclease RBBP8 RBBP8 Antibody
SKU/Catalog Number
A02076-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DNA endonuclease RBBP8 RBBP8 Antibody (Catalog # A02076-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
RBBP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-DNA endonuclease RBBP8 RBBP8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02076-1)
Host
Rabbit
Contents
RBBP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RBBP8 antibody was raised against a 14 amino acid synthetic peptide near the center of human RBBP8. The immunogen is located within amino acids 430 - 480 of RBBP8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SLC29A1 antibody is human specific. SLC29A1 antibody is predicted to not cross-react with other SLC29 proteins.
Reactive Species
A02076-1 is reactive to RBBP8 in Human, Mouse, Rat
Applications
A02076-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
101942 MW
Background of CtIP
RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RBBP8 antibody can be used for detection of RBBP8 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of RBBP8 in mouse spleen tissue lysate with RBBP8 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of RBBP8 in rat spleen tissue with RBBP8 antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of RBBP8 in rat spleen tissue with RBBP8 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For RBBP8 (Source: Uniprot.org, NCBI)
Gene Name
RBBP8
Full Name
DNA endonuclease RBBP8
Weight
101942 MW
Superfamily
COM1/SAE2/CtIP family
Alternative Names
CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; EC 3.1; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RIMSAE2; Sporulation in the absence of SPO11 protein 2 homolog RBBP8 COM1, CTIP, JWDS, RIM, SAE2, SCKL2 RB binding protein 8, endonuclease DNA endonuclease RBBP8|CTBP-interacting protein|RBBP-8|retinoblastoma binding protein 8|sporulation in the absence of SPO11 protein 2 homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RBBP8, check out the RBBP8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RBBP8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DNA endonuclease RBBP8 RBBP8 Antibody (A02076-1)
Hello CJ!
No publications found for A02076-1
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-DNA endonuclease RBBP8 RBBP8 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-DNA endonuclease RBBP8 RBBP8 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
