Key=store_id
Key=entity_id, value=1806
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=PA2222
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2014-05-08 15:19:31
Key=updated_at, value=2024-10-19 05:03:20
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Diubiquitin/UBD Antibody Picoband®
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
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Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1326
Key=yoast_content_score, value=30
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Diubiquitin/UBD Antibody
Key=meta_description, value=Boster Bio Anti-Diubiquitin/UBD Antibody catalog # PA2222. Tested in IHC, WB applications. This antibody reacts with Human. Supplied as 100μg/vial in Lyophilized form antibody.
Key=image, value=/p/a/pa2222-1.jpg
Key=small_image, value=/p/a/pa2222-1.jpg
Key=thumbnail, value=/p/a/pa2222-1.jpg
Key=url_key, value=anti-diubiquitin-antibody-pa2222-boster
Key=url_path, value=anti-diubiquitin-antibody-pa2222-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Anti-Diubiquitin antibody, PA2222, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: SKOV Cell Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: A549 Cell Lysate
Lane 5: SMMC Cell Lysate
Key=small_image_label, value=Anti-Diubiquitin antibody, PA2222, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: SKOV Cell Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: A549 Cell Lysate
Lane 5: SMMC Cell Lysate
Key=thumbnail_label, value=Anti-Diubiquitin antibody, PA2222, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: SKOV Cell Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: A549 Cell Lysate
Lane 5: SMMC Cell Lysate
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Ubiquitin D
Key=gene_full_name, value=Ubiquitin D
Key=uniprot_id, value=O15205
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
Key=source_company, value=Boster PA2222
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=18473 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cell Biology, Defensin, Human Protein, Immunology, Microbiology, Proteasome / Ubiquitin, Protein, Proteolysis/Ubiquitin, Secreted Molecules, Ub-Like Proteins
Key=clonality, value=Polyclonal
Key=swatch_image, value=/m/0/m01357-4-krt18-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=95.9
Key=review_count, value=3
Key=phospho_site
Key=mp_exclude_sitemap, value=No
Key=yoast_focus_keyword, value=CD68 antibody
Key=yoast_facebook_image, value=/p/a/pa1787-2-hexa-primary-antibodies-wb-testing-1_1.jpg
Key=yoast_twitter_image, value=/p/a/pa1787-2-hexa-primary-antibodies-wb-testing-1_1.jpg
Key=cj_related_products, value=Visceral Pain:MA1044|PA2109|PB9209|M01598
Key=description, value=Boster Bio Anti-Diubiquitin/UBD Antibody catalog # PA2222. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Diubiquitin/UBD Antibody catalog # PA2222. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Diubiquitin/UBD Antibody
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Key=background, value=Ubiquitin D, also called UBD or FAT10 is a protein that in humans is encoded by the UBD gene. This gene is mapped to 6p22.1. Ubiquitin-like protein modifier can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. This gene mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It probably functions as a survival factor.
Key=gene_name, value=UBD
Key=synonyms, value=Ubiquitin D;Diubiquitin;Ubiquitin-like protein FAT10;UBD;FAT10;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Nucleus . Cytoplasm . Accumulates in aggresomes under proteasome inhibition conditions.
Key=sequence_similarities, value=Contains 2 ubiquitin-like domains.
Key=tissue_specificity, value= Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland. .
Key=application_notes, value=Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 133199|sc 166553|sc 271289|sc 31849|sc 31850|sc 324974|sc 324975|sc 34870|sc 393630|sc 47721|sc 51081|sc 51082|sc 51086|sc 53509|sc 58449|sc 58450|sc 6085|sc 67202|sc 67203|sc 8017|sc 9133
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the N-terminus of human Diubiquitin, different from the related mouse and rat sequences by five amino acids.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=91 kDa
Key=custom_attribute_2, value=WB: HELA Cell, SKOV Cell, MCF-7 Cell, A549 Cell, SMMC Cell
IHC: Human Intestinal Cancer Tissue, Human Tonsil Tissue
Key=custom_attribute_3, value=BA3363-2
Key=protein_function, value= Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)- associated nephropathy (HIVAN). .
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