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- Table of Contents
Facts about Ubiquitin D.
Conjugation capacity triggered by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2).
Human | |
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Gene Name: | UBD |
Uniprot: | O15205 |
Entrez: | 10537 |
Belongs to: |
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No superfamily |
Diubiquitin; FAT10; FAT10diubiquitin; GABBR1; UBD; UBD-3; ubiquitin D; Ubiquitin-like protein FAT10
Mass (kDA):
18.473 kDA
Human | |
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Location: | 6p22.1 |
Sequence: | 6; NC_000006.12 (29555515..29559732, complement) |
Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland.
Nucleus. Cytoplasm. Accumulates in aggresomes under proteasome inhibition conditions.
PMID: 9368598 by Bates E.E.M., et al. Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells.
PMID: 10200259 by Liu Y.-C., et al. A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2.