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Product Info Summary
| SKU: | A06362 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Density-regulated protein DENR Antibody
SKU/Catalog Number
A06362
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Density-regulated protein DENR Antibody (Catalog # A06362). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Density-regulated protein DENR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06362)
Host
Rabbit
Contents
DENR Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DENR antibody is human, mouse and rat reactive.
Reactive Species
A06362 is reactive to DENR in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
22092 MW
Background of DENR
DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06362 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DENR in human brain tissue lysate with DENR antibody at 1 μg/ml.
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Immunohistochemistry of DENR in rat brain tissue with DENR antibody at 5 μg/mL.
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Immunofluorescence of DENR in rat brain tissue with DENR antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For DENR (Source: Uniprot.org, NCBI)
Gene Name
DENR
Full Name
Density-regulated protein
Weight
22092 MW
Superfamily
DENR family
Alternative Names
DRP, DRP1, SMAP-3, H14, Density-regulated protein, Protein DRP1, DRP DENR DRP, DRP1, SMAP-3 density regulated re-initiation and release factor density-regulated protein|smooth muscle cell associated protein-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DENR, check out the DENR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DENR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Density-regulated protein DENR Antibody (A06362)
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