Density-regulated protein Antibodies

AND DENR ELISA kits, Density-regulated protein Proteins

Many biological assays use antibodies to detect Density-regulated protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Density-regulated protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Density-regulated protein antibodies...

We validate the specificity of these antibodies to Density-regulated protein by testing them on tissues known to express DENR positively and negatively. Browse below to find the DENR antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DENR Infographic by Boster Bio

All DENR Products

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Specificity

Applications

Price

Anti-Density-regulated protein DENR Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A06362
0.1 mg

Density Regulated Protein (DENR) (NM_003677) Human Recombinant Protein

$813
Cat # PROTO43583
20 µg

Anti-DENR Antibody

Human

Flow Cytometry, IF, IHC-P, WB

$299
Cat # M06362
50 µl

Density Regulated Protein (DENR) (NM_003677) Human Over-expression Lysate

Human

$628
Cat # LS008562
100 µg

DENR Overview

Facts about Density-regulated protein.

DENR 3D structure. Source: alphafold

Density-regulated protein (DENR)

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes.

Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Gene Information

Human
Gene Name:	DENR
Uniprot:	O43583
Entrez:	8562

Family

Belongs to:

DENR family

Alternative Names

density-regulated protein; DRP1Protein DRP1; DRPsmooth muscle cell associated protein-3; SMAP-3; Smooth muscle cell-associated protein 3

Molecular Weight

Mass (kDA):
22.092 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (122752824..122771064)

Tissue Specificity

Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.

Diseases

Lymphoma
Cell Transformation, Neoplastic
Neoplasm Metastasis
Leukemogenesis
Charcot-marie-tooth Disease
Hepatitis
Charcot-marie-tooth Disease, Axonal, Autosomal Dominant, Type 2l
Malignant Paraganglionic Neoplasm
Hepatitis C
Teratocarcinoma

Malignant Neoplasms
Neoplasms
Growth Arrest
T-cell Lymphoma

Interacting Proteins

MCTS1
NELFB
UBC

Pathways

Translation
Reverse Transcription
Cell Proliferation
Rrna Modification
Oncogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DENR

References

PMID: 9628587 by Deyo J.E., et al. Drp, a novel protein expressed at high cell density but not during growth arrest.

PMID: 10497265 by Oh J.J., et al. Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells.