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Product Info Summary
| SKU: | A17855 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CUEDC1 Antibody
SKU/Catalog Number
A17855
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CUEDC1 Antibody (Catalog # A17855). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CUEDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CUEDC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A17855)
Host
Rabbit
Contents
CUEDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CUEDC1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CUEDC1. The immunogen is located within amino acids 310 - 360 of CUEDC1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CUEDC1 antibody will not cross-react with CUEDC2.
Reactive Species
A17855 is reactive to CUEDC1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
42258 MW
Background of Cuedc1
The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A17855 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CUEDC1 antibody can be used for detection of CUEDC1 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CUEDC1 in rat liver tissue lysate with CUEDC1 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of CUEDC1 in human liver tissue with CUEDC1 antibody at 2 μg/mL.
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Immunofluorescence of CUEDC1 in human liver tissue with CUEDC1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CUEDC1 (Source: Uniprot.org, NCBI)
Gene Name
CUEDC1
Full Name
CUE domain-containing protein 1
Weight
42258 MW
Alternative Names
CUE domain-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CUEDC1, check out the CUEDC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CUEDC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CUEDC1 Antibody (A17855)
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