Anti-CPT1A Antibody

Product Name

Anti-CPT1A Antibody

View all CPT1A Antibodies

SKU/Catalog Number

A00917

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CPT1A Antibody catalog # A00917. Tested in WB,IHC,ICC/IF,IP applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CPT1A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00917)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human ATF-2 around the phosphorylation site of T73.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00917 is reactive to CPT1A in Human, Mouse, Rat

Applications

A00917 is guaranteed for IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

88368 MW

Background of CPT1A

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.

Gotoh I., J. Biol. Chem. 276:4276-4286(2001).
Bloem L.J., J. Mol. Cell. Cardiol. 33:1739-1750(2001).
Gross E.A., J. Biol. Chem. 277:13873-13882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:100

ICC/IF: 1:50-1:200
IP: 1:50-1:100

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For CPT1A (Source: Uniprot.org, NCBI)

Alternative Names

carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1A (liver); Carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase I, liver; CPT I; CPT1; CPT1-LEC 2.3.1.21; CPTI-L; EC 2.3.1; L-CPT1 CPT1A CPT1, CPT1-L, L-CPT1 carnitine palmitoyltransferase 1A carnitine O-palmitoyltransferase 1, liver isoform|CPT I|CPTI-L|carnitine palmitoyltransferase 1A (liver)|carnitine palmitoyltransferase I, liver

For more info on CPT1A, check out the CPT1A Infographic

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In this infographic, you will see the following information for CPT1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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