CPT1A Antibodies

AND CPT1A ELISA kits, CPT1A Proteins

Many biological assays use antibodies to detect CPT1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CPT1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CPT1A antibodies...

We validate the specificity of these antibodies to CPT1A by testing them on tissues known to express CPT1A positively and negatively. Browse below to find the CPT1A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CPT1A Infographic by Boster Bio

All CPT1A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CPT1A Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A00917
100ul

CPT1A (NM_001876) Human Recombinant Protein

$1062
Cat # PROTP50416
20 µg

Anti-CPT1A Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A00917-3
100 μg/vial

CPT1A (NM_001876) Human Over-expression Lysate

Human

$960
Cat # LS001374
100 µg

CPT1A Overview

Facts about Carnitine O-palmitoyltransferase 1, liver isoform.

CPT1A 3D structure. Source: alphafold

Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)

Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an important step for the adrenal uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.

Gene Information

Human
Gene Name:	CPT1A
Uniprot:	P50416
Entrez:	1374

Family

Belongs to:

carnitine/choline acetyltransferase family

Alternative Names

carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1A (liver); Carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase I, liver; CPT I; CPT1; CPT1-LEC 2.3.1.21; CPTI-L; EC 2.3.1; L-CPT1

Molecular Weight

Mass (kDA):
88.368 kDA

Genomic Context


Human

Location:	11q13.3
Sequence:	11; NC_000011.10 (68754620..68844410, complement)

Tissue Specificity

Strong expression in kidney and heart, and lower in liver and skeletal muscle.

Subcellular Localizations

Mitochondrion outer membrane; Multi-pass membrane protein.

Diseases

Obesity
Insulin Resistance
Hypoglycemia
Fatty Liver
Metabolic Diseases
Diabetes Mellitus
Inflammation
Liver Diseases
Steatohepatitis
Steatosis
Nonalcoholic Fatty Liver Disease
Liver Carcinoma

Insulin Sensitivity
Carcinoma
Atherosclerosis
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Neoplasms
Dyslipidemias

Pathways

Fatty Acid Oxidation
Transport
Pathogenesis
Gluconeogenesis
Cell Proliferation
Energy Homeostasis
Glucose Homeostasis
Fatty Acid Beta-oxidation
Glycolysis
Reverse Transcription
Lipid Oxidation
Cholesterol Efflux
Cell Differentiation

Parturition
Cholesterol Homeostasis
Aging
Translation
Feeding Behavior
Lipid Transport
Localization

PTMs

Oxidation
Phosphorylation

Acetylation
Deacetylation

Methylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPT1A

References

PMID: 7892212 by Britton C.H., et al. Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.

PMID: 12189492 by Gobin S., et al. Organization of the human liver carnitine palmitoyltransferase 1 gene (CPT1A) and identification of novel mutations in hypoketotic hypoglycaemia.